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  1. The Function of Thioredoxin-Binding Protein-2 (TBP-2) in

    May 2, 2018 · Thioredoxin-binding protein-2 (TBP-2) has an important role in the redox system, but it plays a different role in many different diseases (e.g., various cancers, diabetes mellitus …

  2. TXNIP: A key protein in the cellular stress response pathway and a ...

    Jul 3, 2023 · Thioredoxin-interacting protein (TXNIP), which is also known as thioredoxin-binding protein 2 (TBP2), directly interacts with the major antioxidant protein thioredoxin (TRX) and …

  3. TXNIP/TBP-2: A Master Regulator for Glucose Homeostasis

    Aug 18, 2020 · Identification of thioredoxin binding protein-2 (TBP-2), which is currently known as thioredoxin interacting protein (TXNIP), as an important binding partner for thioredoxin (TRX) …

  4. The Function of Thioredoxin-Binding Protein-2 (TBP-2) in …

    May 2, 2018 · TBP-2 not only acts as an antitumor gene that can suppress cell growth at the G 0 /G 1 and G 1 /S phase transitions in different cells by forming different transcriptional repressor …

  5. Thioredoxin binding protein (TBP)-2/Txnip and α-arrestin proteins …

    We identified thioredoxin binding protein (TBP)-2 as a protein that interacts with thioredoxin in the yeast-two hybrid assay. (1) TBP-2 is identical to vitamin D 3 upregulated protein (VDUP)-1 (2) …

  6. Disruption of TBP-2 ameliorates insulin sensitivity and secretion ...

    Nov 23, 2010 · In this study, we show that disruption of thioredoxin binding protein-2 (TBP-2, also called Txnip) in obese mice (ob/ob) dramatically improves hyperglycaemia and glucose …

  7. OVEREXPRESSION OF THIOREDOXIN BINDING PROTEIN (TBP-2) …

    Trx has multi-physiological functions in cells and its bioavailability is negatively controlled through active site binding to a specific thioredoxin binding protein (TBP-2). This paper describes the …

  8. TXNIP (VDUP-1, TBP-2): A major redox regulator commonly suppressed in ...

    Dec 1, 2011 · TXNIP (thioredoxin interacting protein, also known as Vitamin D3 up-regulated protein 1, VDUP-1; thioredoxin binding protein 2, TBP-2), is a key modulator of the redox …

  9. Role of Thioredoxin-Interacting Protein in Diseases and Its

    Mar 9, 2021 · Thioredoxin-interacting protein (TXNIP), widely known as thioredoxin-binding protein 2 (TBP2), is a major binding mediator in the thioredoxin (TXN) antioxidant system, …

  10. Thioredoxin-binding protein-2 (TBP-2) has an important role in the redox system, but it plays a different role in many different diseases (e.g., various cancers, diabetes mellitus (DM), …

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