The inclusion of a sham control in a device trial can reduce bias by facilitating the conduct of double-blinded trials and therefore aid the conduct of high-quality research. This review …

Mar 19, 2018 · This review addresses issues pertaining to the use of sham controls in clinical trials of devices and procedures and provides examples from the literature which demonstrate …

Sham surgery (or placebo surgery) is a faked surgical intervention that omits the step thought to be therapeutically necessary. In clinical trials of surgical interventions, sham surgery is an …

For trials involving sham procedures, clinician-investigators face this ethical conflict in its starkest form; those who conduct trials of pharmaceutical agents have less difficulty in conflating their …

Sham devices, with heating and cooling electronics disconnected, showed equivalent placebo responses compared to devices that moderately heated and cooled, and both devices saw …

Jan 16, 2024 · In clinical trials, a sham is a procedure or device that looks the same and feels the same as an active treatment being tested but doesn’t actually do anything. It’s used as a …

Feb 2, 2006 · We investigated whether a validated sham acupuncture device has a greater placebo effect than an inert pill in people with persistent upper extremity pain due to repetitive …

Feb 18, 2006 · Objective: To investigate whether a sham device (a validated sham acupuncture needle) has a greater placebo effect than an inert pill in patients with persistent arm pain.

Aug 22, 2023 · We highlight salient issues and provide recommendations for the conduct and reporting of sham-controlled device trials in chronic pain. Keywords: Chronic pain; Conduct; …

Oct 13, 2014 · Sham devices can have a larger effect than placebo, should they remain to be under-regulated? Yamama tells us more.