Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) [2] is a strain of coronavirus that causes COVID-19, the respiratory illness responsible for the COVID-19 pandemic. [3] .

The genome of SARS-CoV-2 is comprised of a single-stranded positive-sense RNA . The newly sequenced genome of the SARS-CoV-2 was submitted in the NCBI genome database ( …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as “the novel coronavirus” due to genome variation relative to previously identified coronaviruses, is a …

Jun 24, 2021 · SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded …

Here, I review the current understanding of the molecular biology of coronaviruses and their host interactions, bringing together knowledge of the infection process to aid in the development of …

Jul 1, 2021 · SARS-CoV-2 is an RNA virus whose success as a pathogen relies on its abilities to repurpose host RNA-binding proteins (RBPs) and to evade antiviral RBPs. To uncover the …

Sep 28, 2021 · Here we develop a simplified SPLASH assay and comprehensively map the in vivo RNA-RNA interactome of SARS-CoV-2 genome across viral life cycle.

Jul 19, 2021 · SARS-CoV-2 has a single-stranded, positive-sense RNA (+RNA) genome of ~ 29.9 kb and exhibits significant genetic shift from different isolates.

Mar 31, 2025 · SARS-CoV-2 evolution balances many factors impacting its fitness including entry, immune evasion, packaging, RNA replication, and others. It has been difficult to independently …

The SARS-CoV-2 pandemic has caused a global health crisis due to its high pathogenicity. The SARS-Unique Domain (SUD) in the non-structural protein Nsp3 of SARS-CoV-2 is …