RGS4 - Wikipedia
Regulator of G protein signaling 4 also known as RGP4 is a protein that in humans is encoded by the RGS4 gene. RGP4 regulates G protein signaling. [5] Regulator of G protein signalling …
RGS4 Gene - GeneCards | RGS4 Protein | RGS4 Antibody
Mar 30, 2025 · RGS4 (Regulator Of G Protein Signaling 4) is a Protein Coding gene. Diseases associated with RGS4 include Bipolar Disorder and Schizophrenia. Among its related …
Rgs4 is a regulator of mTOR activity required for motoneuron …
Jun 25, 2021 · The Regulator of G protein signaling 4 (Rgs4) is a member of the RGS proteins superfamily that modulates the activity of G-protein coupled receptors.
Regulator of G protein signaling 4 is a crucial modulator of ...
Regulator of G protein signaling 4 (Rgs4) is a signal transduction protein that controls the function of monoamine, opiate, muscarinic, and other G protein-coupled receptors via interactions with …
Function and regulation of RGS family members in solid tumours: …
In this review, we focus on the G-protein signalling regulator (RGS) family, which includes more than 20 family members. We analysed the classification, basic structure, and major functions …
Allelic Variation in RGS4 Impacts Functional and Structural ...
Regulator of G-protein signaling 4 (RGS4) modulates postsynaptic signal transduction by affecting the kinetics of Gα-GTP binding. Linkage, association, and postmortem studies have implicated …
RGS4 - an overview | ScienceDirect Topics
The N-terminal domain of RGS4 plays a key role in a high-affinity and selective interaction with GPCRs. 111 Full-length RGS4 protein inhibits Ca 2+ response induced by muscarinic ACh …
The therapeutic potential of targeting cardiac RGS4 - PMC
Sep 19, 2023 · We focus on cardiac RGS4 in particular, since this isoform appears to be selectively (among the RGS protein family) upregulated in human heart failure and is also the …
Rgs4 regulator of G-protein signaling 4 [ (house mouse)]
Feb 8, 2025 · Rgs4 regulates vascular endothelial growth factor signaling. These results establish RGS4 and RGS5 as in vivo substrates of the mammalian N-end rule pathway and also …
Mechanism of RGS4, a GTPase-activating Protein for G Protein α …
We have used mutational, biochemical, and structural data to investigate how RGS4, a GAP for heterotrimeric G protein α subunits, stimulates GTP hydrolysis. Many of the residues of RGS4 …