Mar 30, 2025 · PSG2 (Pregnancy Specific Beta-1-Glycoprotein 2) is a Protein Coding gene. Diseases associated with PSG2 include Medullary Thyroid Carcinoma and Secretory Meningioma . Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall .

Human pregnancy-specific glycoproteins (PSGs) are a family of proteins synthesized in large quantities by the placental trophoblast and released into the maternal circulation during pregnancy.

Gene ID: 5670, updated on 4-Jan-2025. The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy.

Nov 23, 2023 · Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes.

Feb 1, 2022 · PSGs are produced by placental trophoblasts and secreted into the maternal bloodstream at high levels where they may regulate maternal immune and vascular functions through receptor binding and modulation of cytokine and chemokine expression and activity.

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Clinical resource with information about PSG2, and available tests. There are links to practice guidelines and authoritative resources like GeneReviews, PubMed, MedlinePlus, PharmGKB and clinicaltrials.gov.

HGNC Approved Gene Symbol: PSG2. Cytogenetic location: 19q13.31 Genomic coordinates (GRCh38) : 19:43,064,209-43,082,701 (from NCBI) The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy.

The PSG2 (pregnancy specific beta-1-glycoprotein 2) is a protein-coding gene located on chromosome 19. PSG2 is a member of the pregnancy-specific glycoprotein (PSG) family, which are proteins produced by the placental trophoblast during pregnancy and released into the maternal bloodstream.

This gene has 4 transcripts (splice variants) and 20 paralogues. A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.