Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. [5] Fruitflies lacking the PAX6 gene …

Dec 25, 2024 · PAX6 (Paired Box 6) is a Protein Coding gene. Diseases associated with PAX6 include Coloboma Of Optic Nerve and Foveal Hypoplasia 1. Among its related pathways are …

The PAX6 gene belongs to a family of genes that play a critical role in the formation of tissues and organs during embryonic development. Learn about this gene and related health conditions.

PAX6 is a key transcription factor involved in brain development and has crucial roles in eye formation and brain development. It regulates the expression of many genes during …

The Pax6 gene was originally identified in mice and humans 30 years ago via genetic analyses of the eye phenotypes. The human PAX6 gene was discovered in patients who suffer from …

There are more than 500 different mutations described to affect PAX6 and its regulatory regions, the majority of which lead to PAX6 haploinsufficiency, causing several ocular and systemic …

Feb 9, 2016 · These findings demonstrate new aspects of the gene regulatory circuitry of Pax6, revealing how it functions to control neuronal development at multiple levels to ensure …

PAX6, a member of the paired box gene family, encodes a transcriptional regulator involved in oculogenesis and other developmental processes. For a discussion of paired box domain …

Nov 30, 2020 · Left eye of a patient with PAX6-related microphthalmia, microcornea and corneal neovascularisation (D). A patient with dominant nystagmus with no iris hypoplasia (E) and …

Here, we show that Pax6, a key transcription factor that controls neurogenesis, also regulates proliferation, differentiation, and migration of astrocytes in the CNS. We first reveal that Pax6 …