Welcome to PRR (Podiatry Residency Resource), the residency management system specifically designed for the podiatric residency community. PRR seamlessly integrates input from residents, program directors, and residency staff.

Mar 6, 2025 · When PRR contains two phosphomimic mutations, PRR 2P, we again observe that the binding curves cluster together (Figure 2 D) and show a greater reduction in tubulin dimer binding capacity compared to PRR WT and PRR 1P variants (Figure 2 F).

N-terminally flanking the MTBR is the proline-rich region (PRR), composed of ∼25% prolines across two subregions, P1 and P2 (Fig. 1). Addition of P2 and R’ to MTBR fragments increases microtubule binding and stimulates polymerization (9–11, 20 – 24).

Here we demonstrate the potential of Tau for LLPS in living cells and identify the Tau proline-rich domain (PRD) as the regulator of condensate formation.

May 13, 2019 · Both full- length tau isoforms and truncated variants are assayed for their ability to bind soluble tubulin and stimulate microtubule polymerization. We describe a novel role for tau’s PRR as an independent tubulin-binding domain with polymerization capacity.

Details Last Updated: 27 June 2022PRR Middle Division in HO Scale

Jul 3, 2017 · The P2 4-6-4: Before the C&O's T1 Texas type was tested, leading to the conception of the J1, the PRR did similar tests with other railroad's engines. One of these was when the PRR tested a Santa Fe 3460 series 4-6-4.

Both PRR and sPRR bind prorenin and renin and increase ANG II generation, which, in turn, stimulates angiotensin type 1 receptor (AT 1 R) and influences AQP2 trafficking. PRR influences Na + homeostasis and blood pressure regulation via …

Apr 1, 2019 · Prolactin-releasing peptide2 (PrRP2) belongs to the RFamide peptide group and is a paralog of prolactin-releasing peptide (PrRP). Recent studies demonstrated that PrRP2, but not PrRP, regulates prolactin release in teleosts.

PrRP2 is a potent stimulator of prolactin in teleosts, but has a lesser effect in amphibians and chickens. As in PrRP, PrRP2 is related to energy homeostasis in teleosts and chickens. The physiological functions of PrRP and PrRP2 may have changed through evolution. A. …