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  1. Protein Phosphatase 2A, a Negative Regulator of the ERK

    Oct 1, 2004 · Protein phosphatase 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including those …

  2. B56‐containing PP2A dephosphorylate ERK and their activity is ...

    Feb 2, 2006 · The protein phosphatase 2A (PP2A) acts on several kinases in the extracellular signal‐regulated kinase (ERK) signaling pathway but whether a specific holoenzyme …

  3. Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause …

    The CDK9‐Src‐PP2A network drove rapid and persistent phosphorylation of ERK and unleashed the production of complement C1r and C3, leading to complement activation and …

  4. Protein phosphatase 2A (PP2A) is a family of mamma-lian serine/threonine phosphatases that is involved in the control of many cellular functions including those mediated by extracellular …

  5. Inhibition of PP2A enhances the osteogenic differentiation of …

    Sep 15, 2020 · Key findings: PP2A activity was decreased both in calcified aortic valves and human VICs under osteogenic induction. The PP2A inhibitor LB100 aggravated the aortic …

  6. Protein phosphatase 2A, a negative regulator of the ERK

    Oct 1, 2004 · Protein phosphatase 2A (PP2A) is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including those …

  7. Raf-independent, PP2A-dependent MEK Activation in Response to ERK

    Aug 7, 2009 · PP2A is known to regulate c-Raf-MEK-ERK signaling through both positive and negative mechanisms via a feedback loop [22,24]. Ras-GTP induces kinase suppressor of …

  8. B56-containing PP2A dephosphorylate ERK and their activity

    The protein phosphatase 2A (PP2A) acts on several kinases in the extracellular signal-regulated kinase (ERK) signaling pathway but whether a specific holoenzyme dephosphorylates ERK …

  9. A cholesterol-regulated PP2A/HePTP complex with dual specificity …

    Jun 2, 2003 · The existence of a cholesterol-regulated HePTP/PP2A activity provides a molecular explanation for why ERK activity is sensitive to membrane cholesterol levels, and raises the …

  10. Protein Phosphatase 2A, a Negative Regulator of the ERK

    PP2A is an important negative regulator of the extracellular signal-regulated kinase (ERK) signaling pathway and is involved in the control of many cellular functions including …

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