SignalSilence® NF-kappaB p65 siRNA from Cell Signaling Technology allows the researcher to specifically inhibit NF-kappaB p65 expression using RNA interference, a method in which gene expression can be selectively silenced through the delivery …

RELA/NFκB p65 siRNA (h), shRNA and Lentiviral Particle Gene Silencers designed to knockdown human NFκB p65 gene expression. Cited in 212 publications.

Mar 30, 2017 · Here, we show that RelA/p65 functions as a core fibrogenic regulator in tendon adhesion and that its inhibition exerts an anti-fibrogenic effect on peritendinous adhesion.

By delivering NF-κB p65 siRNA, the p65 siRNA/LPCE complex showed a therapeutic effect quite quickly and demonstrated strong arthritic inhibition ability in a CIA mouse model. Our results suggest that the LPCE functionalized micelle is an advanced candidate for …

Feb 15, 2022 · Here, we assess the impact of silica-coated calcium phosphate nanoparticles carrying encapsulated siRNA against NF-κB p65 on a murine model of colitis. To this end, nanoparticles were injected intravenously (2.0 mg siRNA/kg body weight) into mice after colitis induction with dextran sulfate sodium or healthy ones.

Sep 1, 2021 · We investigated the role of cationic silica-coated calcium phosphate nanoparticles (spherical, diameter by SEM 50–60 nm; zeta potential about +26 mV; stabilized by polyethyleneimine) carrying encapsulated siRNA against NF-κB …

3 days ago · SignalSilence ® NF-κB p65 siRNA II from Cell Signaling Technology (CST) allows the researcher to specifically inhibit NF-κB p65 expression using RNA interference, a method whereby gene expression can be selectively silenced through the delivery of double stranded RNA molecules into the cell.

Jan 4, 2021 · We established that si-P65 remarkably reduced the expression of STING-induced senescence-associated (p16INK4a and p21), and apoptosis-associated (BAX, Cyto-c, as well as cleaved-caspase-3 ...

Oct 26, 2023 · To enhance the therapeutic effect of buformin, six p65 siRNA molecules are loaded onto the DNA nanoprism. Both buformin and p65 siRNA demonstrated remarkable inhibition of NLRP3-mediated pyroptosis.

RELA/NFκB p65 siRNA (h2), shRNA and Lentiviral Particle Gene Silencers designed to knockdown human NFκB p65 gene expression. Cited in 8 publications.