Ouabain / w ɑː ˈ b ɑː ɪ n / [1] or / ˈ w ɑː b eɪ n, ˈ w æ-/ (from Somali waabaayo, "arrow poison" through French ouabaïo) also known as g-strophanthin, is a plant derived toxic substance that …

Ouabain is a steroid hormone that is a multi-hydroxylated alpha-L-rhamnosyl cardenoloide. It binds to and inhibits the plasma membrane Na(+)/K(+)-ATPase (sodium pump). It has been …

Jun 13, 2005 · Ouabain DrugBank Accession Number DB01092 Background. A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …

Ouabain, the ligand of Na,K-ATPase, is a steroid derivative that, unlike other steroid hormones, binds specifically to an integral plasma membrane protein. Ouabain derivatives have been …

Ouabain (OUA) is an exogenous hormone analog with potent Na/K-ATPase inhibitory effects, and consequent induction of depolarization and neuronal excitation. A single …

In this brief article, we summarize recent reports about endogenous ouabain (EO), a cardiotonic steroid (CTS). This includes analysis of mammalian EO, the discovery of EO isomers, …

Since the discovery of ouabain as a cardiotonic steroid hormone present in higher mammals, research about it has progressed rapidly and several of its physiological and pharmacological …

Dec 30, 2013 · Ouabain binds to and inhibits the transport activity of the Na + /K + /ATPase (i.e., sodium pump). Ouabain is plant derived and belongs to the class of drugs referred to as …

Jan 7, 2025 · Ouabain, a cardiac glycoside similar to digitoxin, is used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular …

Ouabain, also called strophanthin or strophanthus, comes from the seeds of a plant in Africa. It has been used in Germany for decades to successfully treat heart disease. FAIM’s founders …