Myb genes are part of a large gene family of transcription factors found in animals and plants. In humans, it includes Myb proto-oncogene like 1 and Myb-related protein B in addition to MYB proper.

Mar 30, 2025 · MYB (MYB Proto-Oncogene, Transcription Factor) is a Protein Coding gene. Diseases associated with MYB include Adenoid Cystic Carcinoma and Angiocentric Glioma. Among its related pathways are Gene expression (Transcription) and ESR-mediated signaling.

Feb 26, 2021 · In humans, the MYB gene family is composed of three members: MYB, MYBL1 and MYBL2, encoding the transcription factors MYB, MYBL1, and MYBL2 (also known as c-MYB, A-MYB, and B-MYB),...

The MYB protein is a pivotal player in the cellular transcriptional network, influencing major important processes such as cell proliferation, differentiation, and apoptosis. Because of its role in oncogenesis, MYB is now a compelling target for therapeutic interventions in cancer research.

The MYB gene is a master regulator of hematopoietic system development and function and deregulated MYB expression in humans leads to a constellation of hematological and non-hematological malignancies.

MYB transcription factors are involved in plant development, secondary metabolism, hormone signal transduction, disease resistance and abiotic stress tolerance. A comparative analysis of MYB family genes in rice and Arabidopsis will help reveal the …

MYB is a master regulator and pioneer factor highly expressed in hematopoietic progenitor cells (HPCs) where it contributes to the reprogramming processes operating during hematopoietic development. MYB plays a complex role being involved in …

Apr 7, 2025 · Title: MYB alternative promoter activity is increased in adenoid cystic carcinoma metastases and is associated with a specific gene expression signature. MYB/LINC00092 regulatory axis promotes the progression of papillary thyroid carcinoma.

May 13, 1999 · The myb gene family consists of three members, named A, B and c-myb which encode nuclear proteins that function as transcriptional transactivators.

May 13, 1999 · The myb gene family consists of three members, named A, B and c-myb which encode nuclear proteins that function as transcriptional transactivators. Proteins encoded by these three genes exhibit a tripartate structure with an N-terminal DNA-binding domain, a central transactivation domain and a C-ter …