Using a monospecific rabbit antiserum raised against a bacterial fusion protein, we identified the UL7 gene product of the neurotropic alphaherpesvirus pseudorabies virus (PrV).

Here, we report on UL7, a novel HCMV heavily glycosylated transmembrane protein, containing an Ig-like domain that exhibits remarkable amino acid similarity to CD229, a cell-surface molecule of the signalling lymphocyte-activation molecule (SLAM) family involved in leukocyte activation.

Oct 28, 2014 · In the current study, mutational analysis of the HCMV genome identified UL7 as the viral gene responsible for induction of AG factors during HCMV infection. UL7 is a late gene encoding a transmembrane protein that is cleaved to produce a small soluble protein secreted from the cell (13).

Jan 6, 2021 · Human cytomegalovirus (HCMV) infection of myeloid lineage cells, such as CD34 + hematopoietic progenitor cells (HPCs) or monocytes, results in the upregulation of antiapoptotic cellular proteins that protect the newly infected cells from programmed cell death.

Jan 6, 2021 · Human cytomegalovirus (HCMV) infection of myeloid lineage cells, such as CD34 + hematopoietic progenitor cells (HPCs) or monocytes, results in the upregulation of antiapoptotic cellular proteins that protect the newly infected cells from programmed cell death.

Apr 24, 2018 · HCMV encodes UL7 that our group has shown is secreted from infected cells and induces angiogenesis. In this study, we show that UL7 is a ligand for Fms-like tyrosine kinase 3 receptor (Flt-3R), a well-known critical factor in HPC differentiation.

Our group previously discovered a viral hematopoietic cytokine (pUL7) that promotes cellular differentiation and viral reactivation. Here, we show that the UL7-related RL11 family member UL8 is also required for efficient viral reactivation in CD34 + HPCs by interacting with components of the (Wnt)/β-catenin pathway. Pull-down experiments ...

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Aug 9, 2014 · "N'wah" is reserved for Foreigners or Slaves.

Oct 28, 2003 · Daiwa used to make a GREAT little spinning reel called the UL7 , does anyone know what replaced it ? I can't seem to find anything even close to it, a "reel" workhorse , I still use 2 that I bought in the mid- 80's and just can't part …