Our data provide detailed information on how mPFC afferent fibers project through the brain in a characteristic manner, leading to the successful design of a slice preparation that allows for identification and activation of the hippocampal projection.

Mar 15, 2006 · We present an anatomical, electrophysiological, and pharmacological characterization of a novel brain slice preparation (BLA-mPFC) to investigate basolateral amygdala synaptic input to rat layer V medial prefrontal cortex pyramidal neurons.

Jul 1, 2021 · The rodent medial prefrontal cortex (mPFC) shows key differences from sensory cortex in the composition and organization of local and long-range circuits.

Jul 1, 2019 · Coronal slices (thickness 300 µm) containing both the prelimbic and the infralimbic subregions of the prefrontal cortex were cut in oxygenated ice-cold protective aCSF and subsequently...

May 31, 2024 · Whole-cell patch-clamp recordings in acute mouse brain slices revealed both monosynaptic excitatory responses and disynaptic feedforward inhibition for both Re-mPFC and Re-dCA1 pathways. However, we also identified a …

To map the critical period of SSA in the mPFC, acute coronal brain slices were imaged using the calcium‐dependent indicator Fura‐2 from birth (P0) to the end of the second postnatal week.

Mar 15, 2006 · We present an anatomical, electrophysiological, and pharmacological characterization of a novel brain slice preparation (BLA-mPFC) to investigate basolateral amygdala synaptic input to rat layer V medial prefrontal cortex pyramidal neurons.

we describe the cellular diversity of the rodent mPFC, the impact of long-range afferents, and the specificity of local microcircuits. We highlight similarities with and differences between other cortical areas, illustrating how the circuit organization of the …

May 21, 2019 · Voltage imaging of network responses in mPFC slices from hM3Dq-expressing mice revealed stronger vHIP inputs and, surprisingly, weaker responses evoked by stimulation of intracortical inputs (which were not chemogenitically manipulated), resembling the responses observed in Mecp2 KO mice.

Some variations exist in the literature with regards to the precise definition of the rodent mPFC, and for the purpose of this article, the mPFC refers to the collection of anterior cingulate (ACC), prelimbic (PL) and infralimbic (IL) cortices.