Pupils are the black centers of your eyes. The medical term for small, constricted pupils is miosis. Eye miosis can be caused by many things, including using opioids or having a stroke.

May 15, 2021 · Miotic and mydriatic drops work by acting on these different muscles of the iris. The drops are able to control pupil size by targeting two parts of the autonomic nervous system: the sympathetic and parasympathetic systems.

Miosis from bright light pointed directly at the eye. Pupil measured 2.3 mm in diameter. Miosis, or myosis (from Ancient Greek μύειν (múein) 'to close the eyes'), is excessive constriction of the pupil. [1][2][3][4] The opposite condition, mydriasis, is the dilation of the pupil.

Feb 7, 2025 · If your pupils stay small even in dim light, it can be a sign that things in your eye aren't working the way they should. This is called abnormal miosis, and it can happen in one or both of...

Jan 26, 2021 · Miosis occurs when the pupil of your eye shrinks and becomes very small, like a pinpoint. It may be caused by medications, injury, illness and even aging.

Feb 21, 2019 · Miosis means excessive constriction (shrinking) of your pupil. In miosis, the diameter of the pupil is less than 2 millimeters (mm), or just over 1/16th of an inch. The pupil is the...

Oct 11, 2024 · Mitomycin is an antimetabolite medicine that interferes with the growth and spread of certain cells in the body. Mitomycin ophthalmic (for the eyes) is used during glaucoma surgery. Mitomycin ophthalmic may also be used for purposes not listed in this medication guide.

Hence, the most common manifestations of mitochondrial disorders are progressive external ophthalmoplegia, macular pattern dystrophy, pigmentary retinopathy, optic neuropathy and retrochiasmal visual field loss.

Ophthalmic direct-acting miotics are used to contract the eye’s ciliary muscle and the sphincter muscle encircling the iris, which constricts the pupil, improves aqueous humor drainage and reduces intraocular pressure.

In this review, we outline the mechanistic basis of ROS-induced mtDNA dysfunction and the mitochondrial/oxidative stress theory of aging in relation to the ocular system.