Jan 1, 2011 · Muscular dystrophy (MD) connotes a heterogeneous group of inherited disorders characterized by progressive wasting and weakness of the skeletal muscles. In several forms of MD, cardiac dysfunction occurs, and cardiac disease may even be the predominant manifestation of the underlying genetic myopathy.

Aug 24, 2017 · In this statement, we provide background on several NMDs in which there is cardiac involvement, highlighting unique features of NMD-associated myocardial disease that require clinicians to tailor their approach to prevention and treatment of heart failure.

This session will provide patients and their caregivers with an understanding of how neuromuscular conditions affect the heart, as well as practical strategies for managing and monitoring heart health.

Cardiac disease in MMD1, Groh says, is nearly always conduction disturbance, resulting from the gradual replacement of the heart’s conductive tissue with scar tissue, a process known as cardiac fibrosis.

Myotonic dystrophy (DM) is an autosomal dominant muscular dystrophy that produces progressive skeletal muscle wasting and cardiac conduction abnormalities; multisystem manifestations include cataracts, testicular failure, hypogammaglobulinemia and …

Duchenne and Becker muscular dystrophy (DMD/BMD) are X-linked muscular diseases responsible for over 80% of all muscular dystrophies. Cardiac disease is a common manifestation, not necessarily related to the degree of skeletal myopathy; it may be ...

Jul 10, 2024 · Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X-linked muscle-wasting diseases cumulatively affecting 1 in 5000 males, with DMD being 3-fold more common than BMD. 1 The cardiac and cardiac electrophysiologic manifestations of both conditions play a significant role in prognosis, disease progression, and mortality ...

Duchenne muscular dystrophy (DMD) results in a progressive cardiomyopathy that produces significant morbidity and mortality. To improve the quality of life in patients with DMD, cardiac care is focused on surveillance and management, with the goal of slowing the onset and progression of heart failure complications.

• Early recognition of patients at risk for cardiac disease, integration of a cardiologist, and strong coordination of multidisciplinary care can optimize outcomes • This document highlights key points from an MDA webinar with a cardiologist with NMD care expertise. View companion webinar here Cardiac Manifestations of Common Genetic NMDs

Mar 12, 2008 · Duchenne Muscular Dystrophy (DMD) patients. become symptomatic before 5 years of age; present a loss of ambulation between ages 7 and 12; cardiomyopathy and respiratory muscle dysfunction typically occur several years after the onset of neuromuscular symptoms and contributes to death.