MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. It is the homologue of the human "G/T binding …

Jul 15, 2023 · This information explains how having a mutation in the MSH6 gene may affect you and your family.

Mar 24, 2025 · MSH6 inherited mutations (Lynch Syndrome) may affect your options for cancer prevention, detection and treatment. FORCE is here to guide you.

The MSH6 gene provides instructions for making a protein that plays an essential role in repairing DNA. This protein helps fix errors that are made when DNA is copied (DNA replication) in …

MSH6 is a type of tumor suppressor gene known as a DNA mismatch repair gene. When working correctly, tumor suppressor genes help to prevent cancer by controlling the growth and …

Mar 24, 2025 · MSH6 mutations increase the risk for colorectal, endometrial and other types of cancer listed in the table below. Experts at the National Comprehensive Cancer Network …

People with an MSH6 mutation who have been diagnosed with cancer may benefit from biomarker testing and may qualify for clinical trials looking for more effective treatments for …

Mar 30, 2025 · MSH6 (MutS Homolog 6) is a Protein Coding gene. Diseases associated with MSH6 include Lynch Syndrome 5 and Endometrial Cancer. Among its related pathways are …

Here, we briefly describe the disorders that are related to MMR deficiency, as well as the structure and function of MSH6. Moreover, we review the functional assays that are used to examine …

This review will focus on molecular mechanisms associated with mismatch binding, as well as emerging evidence that MutSα and in particular, MSH6, is a key protein in MMR-dependent …