DNA replication licensing factor MCM7 is a protein that in humans is encoded by the MCM7 gene. [5] The protein encoded by this gene is one of the highly conserved mini-chromosome …

Mar 30, 2025 · MCM7 (Minichromosome Maintenance Complex Component 7) is a Protein Coding gene. Diseases associated with MCM7 include Anisometropia and Farsightedness. …

Feb 9, 2017 · Mechanistically, knockdown of MCM7 significantly inhibited cellular proliferation in vitro and HCC tumorigenicity in vivo. Cyclin D1 was proved to be regulated by MCM7–MAPK …

Mar 2, 2021 · Through exome and chromium genome sequencing, supported by functional studies, we identify biallelic pathogenic variants in MCM7 and a strong candidate biallelic …

Homozygous mutation in MCM7 causes autosomal recessive primary microcephaly and intellectual disability. MCM7 affects the cisplatin resistance of liver cancer cells and the …

Miniature chromosome maintenance 7 (MCM7) is an essential component of DNA replication licensing complex. Recent studies indicate that MCM7 is amplified and overexpressed in a …

MCM7 knockdown significantly inhibited cell proliferation via suppressing cyclin D1 expression in HCC cell lines, suggesting that MCM7 might be a potential therapeutic target for HCC. In this …

Jun 17, 2024 · Tandem affinity purification and mass spectrometry analysis identify minichromosome maintenance complex component 7 isoform 1 (MCM7), HIV-1 Gag, Gag/Pol, …

Since MCM7 expression was generally low in a number of normal tissues we examined, MCM7 has the characteristics of an ideal candidate for molecular targeted cancer therapy in various …

Jul 5, 2013 · MCM7 is one of the subunits of the MCM2-7 complex that plays a critical role in DNA replication initiation and cell proliferation of eukaryotic cells. After forming the pre-replication …