LPS-stimulated NF-κB p65 dynamic response marks the ... - PubMed
The kinetics of the responses of proinflammatory TNFα, anti-inflammatory IL-10, and inflammatory master regulator NF-κB elicited by lipopolysaccharide (LPS) may be critical determinants of …
Baicalin prevents LPS-induced activation of TLR4/NF-κB p65
May 26, 2020 · Previous studies have shown that baicalin, an active ingredient of the Chinese traditional medicine Huangqin, attenuates LPS-induced inflammation by inhibiting the …
Baicalin prevents LPS-induced activation of TLR4/NF-κB p65 ... - PubMed
Exposure to LPS (1 μg/mL) induced inflammatory responses in RAW264.7 cells, evidenced by marked increases in the expression of MHC II molecules and the secretion of NO and IL-6, …
Lipopolysaccharide-induced NF-κB nuclear translocation is …
May 3, 2017 · LPS activates TLR4 at the cell surface resulting in MyD88 activation via Mal. LPS also promotes TLR4 endocytosis following association with CD14 in the presence of the LPS …
IKKβ Plays an Essential Role in the Phosphorylation of RelA/p65 on ...
Jun 1, 2003 · The LPS-induced p65 phosphorylation on serine 536 was independent of the phosphatidylinositol 3′-kinase/Akt signaling pathway. Furthermore, we found that the …
NOS2 regulation of LPS-induced airway inflammation via S …
We now show that aerosolized LPS induces NOS2 expression in the respiratory epithelium concomitant with an increase in lung SNO-p65 levels and a decrease in airway NF-κB activity. …
Deficient chaperone-mediated autophagy facilitates LPS-induced ...
Oct 6, 2023 · Upon stimulation with lipopolysaccharide (LPS), the transcription factor NF-κB/p65 enters the nucleus to transactivate genes that express proinflammatory cytokines and NLR …
LPS‐stimulated NF‐κB p65 dynamic response marks the initiation …
Nov 13, 2018 · LPS stimulation of NF-κB nuclear translocation, cytosolic IκBα degradation, and nuclear NF-κB p65 oligonucleotide binding. (A) Western blot analysis of fractionated nuclear …
NF-κB p65 and TCF-4 interactions are associated with LPS …
Jul 1, 2024 · NF-κB p65 and TCF-4 binding in the nucleus was associated with LPS stimulation. Proinflammatory cytokine plays a central role in host defense and acute inflammatory responses.
Transcriptional profiling of the LPS induced NF-κB response in ...
Jan 12, 2007 · In this report, we have investigated and compared the LPS response in macrophage derived cell lines and peripheral blood mononuclear cell (PBMC) derived …