Lysophosphatidylcholines are produced within cells mainly by the enzyme phospholipase A2, which removes one of the fatty acid groups from phosphatidylcholine to produce LPC. [2] Among other properties, they activate endothelial cells during early atherosclerosis .

lpc determines the coefficients of a forward linear predictor by minimizing the prediction error in the least squares sense. It has applications in filter design and speech coding. lpc uses the autocorrelation method of autoregressive (AR) modeling to find the filter coefficients.

LPC is a ligand of GPR119 and facilitates glucose-induced insulin secretion of pancreatic beta-cells [148]. In the liver, LPC downregulated genes involved in fatty acid oxidation and upregulated genes for cholesterol biosynthesis.

Apr 15, 2020 · Lysophosphatidylcholine (LPC) is the main component of oxidatively damaged low-density lipoprotein (oxLDL). LPC originates from the cleavage of phosphatidylcholine by phospholipase A2 (PLA2). LPC plays a biological role by binding to G protein-coupled receptors and Toll-like receptors.

LPC is a ligand for specific G protein-coupled signalling receptors and activates several second messengers. LPC is also a major phospholipid component of oxidized low-density lipoproteins (Ox-LDL) and is implicated as a critical factor in the atherogenic activity of Ox-LDL.

Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid generated by pathological activities. LPC is also a major phospholipid component of oxidized low-density lipoprotein (Ox-LDL). LPC plays an important role in atherosclerosis and inflammatory diseases by altering various functions in a number of cell-types, including endothelial ...

Based almost exclusively on studies of LPC effects on cultured cells, LPC thus generated is thought to influence the function of immunoregulatory cells to modulate inflammatory processes and immune responses.

Lysophosphatidylcholine (LPC) is a major plasma lipid that has been recognized as an important cell signalling molecule produced under physiological conditions by the action of phospholipase A 2 on phosphatidylcholine. LPC transports glycerophospholipid components such as fatty acids, phosphatidylglycerol and choline between tissues.

Mar 6, 2019 · Lysophosphatidylcholine (LPC) is increasingly recognized as a key marker/factor positively associated with cardiovascular and neurodegenerative diseases.

Apr 15, 2020 · The biological function of LPC in different cells promotes the formation of atherosclerotic plaques, aggravates inflammation, enhances anti-infective responses, regulates blood glucose, and affects the invasion and metastasis of tumours.