Role of the JIP4 scaffold protein in the regulation of mitogen ...
Like other members of the JIP family of scaffold proteins, JIP4 binds JNK and also the light chain of the microtubule motor protein kinesin-1. However, the function of JIP4 appears to be …
Role of the JIP4 Scaffold Protein in the Regulation of Mitogen ...
The c-Jun NH2-terminal kinase (JNK)-interacting protein (JIP) group of scaffold proteins (JIP1, JIP2, and JIP3) can interact with components of the JNK signaling pathway and potently …
The role of scaffold proteins in JNK signalling - PMC
JIP‐4 and SPAG9 show fundamental differences in organ expression. JIP‐4 is mainly expressed in the brain, heart, liver, kidney and testis, whereas SPAG9 is only expressed in haploid germ …
JIP-4 Antibody (H-8) | SCBT - Santa Cruz Biotechnology
JIP-4 Antibody (H-8) is an IgG κ mouse monoclonal JIP-4 antibody (also designated JIP-4 antibody) that detects the JIP-4 protein of mouse, rat and human origin by WB, IP, IF, IHC (P) …
JIP-4 | definition of JIP-4 by Medical dictionary
A gene on chromosome 17q21.33 that encodes sperm-associated antigen 9, a member of the JNK-interacting protein (JIP) group of scaffold proteins, which selectively mediates JNK …
SPAG9 Gene - GeneCards | JIP4 Protein | JIP4 Antibody
Mar 30, 2025 · SPAG9 (Sperm Associated Antigen 9) is a Protein Coding gene. Diseases associated with SPAG9 include Retinitis Pigmentosa 42 and Subacute Leukemia. Among its …
JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to ...
Jul 20, 2021 · Here, we report that JIP4 (officially known as SPAG9), a protein previously described to bind to microtubule motors, is recruited to tubulating subdomains on …
JNK-interacting protein 4 is a central molecule for lysosomal ...
Here, we outline recent findings on the mechanisms of lysosomal trafficking by focusing on adapter protein c-Jun NH 2 -terminal kinase-interacting protein (JIP) 4, which plays a central …
O60271 - UniProt
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling …
EGFR/JIP-4/JNK2 Signaling Attenuates Cetuximab-Mediated ...
Jan 2, 2013 · Using phosphoproteome arrays, we observed strong induction of JNK2 phosphorylation potentially resulting from cetuximab-inhibited EGFR through c-jun-NH 2 …