The interleukin 4 receptor is a type I cytokine receptor. It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines with …

Mar 30, 2025 · IL4R (Interleukin 4 Receptor) is a Protein Coding gene. Diseases associated with IL4R include Ige Responsiveness, Atopic and Human Immunodeficiency Virus Type 1. Among …

We sought to provide a comprehensive analysis of the redundant and distinct roles of IL-4 and IL-13 in type 2 inflammation and report dupilumab mechanisms of action. Methods: Using …

Feb 8, 2025 · Gene target information for IL4R - interleukin 4 receptor (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Mar 6, 2020 · Interleukin (IL)-4 and IL-13 are well known for their key roles in type 2 immune responses, which result in resistance to helminth parasites and inactivation of toxins.

Receptor for both interleukin 4 and interleukin 13 (PubMed: 17030238). Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 …

Feb 8, 2025 · Clinical resource with information about IL4R, A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci., A …

Here we describe our current understanding of the organization of the IL-4 receptor, of the signaling pathways that are induced as a result of receptor occupancy, and of the various …

Dec 1, 2016 · Interleukin-4 is the prime anti-inflammatory cytokine involved in cell proliferation, gene expression and apoptosis. α chain of IL-4R is also a fundamental part of IL-13R hence, …

Gene ID: 3566, updated on 8-Feb-2025. This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to …