Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. [4] [5] [6] IL-13 was first cloned in 1993 and is located on chromosome 5q31.1 with a length of 1.4kb. [4] It has a …

Interleukin 13 (IL-13) is a cytokine that is responsible for promoting Th2 responses in humans and is released by T cells, mast cells, and eosinophils. It is typically associated with allergic …

Recently, IL-13 has been suggested to be the key T2 cytokine driving inflammation in the periphery, while IL-4 may merely have a central effect.

IL-13 is an immunoregulatory cytokine secreted predominantly by activated T (H)2 cells. Over the past several years, it has become evident that IL-13 is a key mediator in the pathogenesis of …

Interleukin 13 (IL-13) is an effector cytokine partially sharing the signaling pathways with IL-4 due to the utilization of a common receptor system (IL-4 receptor type II).

Mar 30, 2025 · IL13 (Interleukin 13) is a Protein Coding gene. Diseases associated with IL13 include Allergic Rhinitis and Asthma. Among its related pathways are MIF Mediated …

Apr 7, 2025 · It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the …

Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and …

Interleukin-13 (IL-13) was previously thought to be a redundant presence of IL-4, but in recent years its role in immunity, inflammation, fibrosis, and allergic diseases has become …

Jan 13, 2023 · We have identified IL-13 and its receptor IL-13Ra1 as neuronal, synaptic proteins in mouse, rat, and human brains, whose engagement upregulates the phosphorylation of …