Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts …

Interleukin 6 (IL-6), promptly and transiently produced in response to infections and tissue injuries, contributes to host defense through the stimulation of acute phase responses, hematopoiesis, …

Oct 1, 2022 · Recently, IL-6 secretion was shown to form the backbone of hypercytokinemia seen in the Coronavirus disease 2019 (COVID-19)-associated hyperinflammation and multiorgan …

IL-6: a nexus for immune responses and disease Keywords: cytokine storm of COVID-19, IL-6 amplifier, local initiation model, NF-κB, STAT3

Anti-interleukin-6 agents are a class of therapeutics. Interleukin 6 is a cytokine relevant to many inflammatory diseases and many cancers. [1] Hence, anti-IL6 agents have been sought. …

Jul 9, 2024 · INTRODUCTION Interleukin 6 (IL-6) is a potent proinflammatory mediator that is important in immune defense and in immune-mediated disease.

In this review, we will discuss how the IL-6 signaling pathway influences the adaptive immune response, promotes autoimmunity and how blocking different aspects of this pathway is …

Interleukin-6 (IL-6) is a member of the pro-inflammatory cytokine family, induces the expression of a variety of proteins responsible for acute inflammation, and plays an important role in the …

Interleukin-6 (IL-6) is a prototypical cytokine for maintaining homeostasis. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host …

Interleukin-6 (IL-6) is a pleiotropic cytokine originally discovered by the Japanese immunologist Kishimoto's group and encoded by the IL-6 gene in humans (Ferguson-Smith et al., 1988), …