Interstate 81 (I-81) is a north–south (physically northeast–southwest) Interstate Highway in the eastern part of the United States.

The I-81 Interstate 81 Highway is a major automotive & trucking transportation corridor and interstate highway that travels generally in a north/northeast-south/southwest direction along …

14 hours ago · I-81 traffic, road conditions, accidents and constructions. Current driving time, average speed and traffic delays in each state.

Interstate 81 travels much of the Appalachian Mountains northward from Interstate 40 east of Knoxville to the Canadian Border north of Watertown, New York.

12 hours ago · The centerpiece of this project is tearing down the section of I-81 through downtown Syracuse. That won't happen until the end of 2026. For now, work continues on the …

In Pennsylvania, I-81 runs for 232.76 miles (374.59 km) from the Maryland state line northeast to the New York state line near Hallstead and is called the American Legion Memorial Highway. …

Interstate 81 is over 800 miles of history, natural wonders, and quirky tourist attractions. Beginning just northeast of Knoxville, Tennessee, I-81 travels through six states, and ends at the border …

Interstate 81 (abbreviated I-81) is an interstate highway in the eastern part of the United States. Its southern terminus is at Interstate 40 near Dandridge, Tennessee; its northern terminus is …

Interstate 81 highway connects the cities of Tennessee, Virginia, West Virginia, Maryland, Pennsylvania, New York state. Detailed map interstate route I-81 with interchange and exit …

I-81 Traffic Maps ... Click highlighted cities on map or larger text list below ... Select region for local traffic conditions maps ...