Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. [1] [2] These bis-benzimides were originally developed by Hoechst AG, which numbered all their compounds so that the dye Hoechst 33342 is the 33,342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580.

Hoechst AG (German pronunciation: [ˈhøːçst]) was a German chemicals, later life sciences, company that became Aventis Deutschland after its merger with France's Rhône-Poulenc S.A. in 1999. With the new company's 2004 merger with Sanofi-Synthélabo , it became a subsidiary of the resulting Sanofi-Aventis pharmaceuticals group.

Invitrogen Hoechst 33342 nucleic acid stain is a popular cell-permeant nuclear counterstain that emits blue fluorescence when bound to dsDNA. This dye is often used to distinguish condensed pycnotic nuclei in apoptotic cells and for cell cycle studies in combination with BrdU.

Hoechst dyes are non-intercalating, binding specifically to the minor groove of DNA at A–T-rich regions. This unique binding mechanism allows for precise and reliable DNA staining. Whether you're working with living or fixed cells, our Hoechst dyes are compatible with immunohistochemistry applications.

The name Höchst became known throughout the world for the chemical and pharmaceutical corporation Hoechst AG which was established in 1863.

Performing nuclear staining with DAPI or Hoechst? Check out Biotium's detailed Hoechst & DAPI staining protocols for staining live cells or fixed cells & tissues.

The first plan of action was to double the U.S. sales force, and also to target hospitals, the major customers for ethical drugs. Early in the decade, Hoechst presented Harvard's teaching hospital, Massachusetts General, with a history-making US$70 million grant to fund cooperative genetic research. Hoechst acquired New Jersey-based Celanese in ...

Apr 18, 2018 · Hoechst are non-intercalating dyes that bind the DNA minor groove at A–T-rich regions (Figure 1b). Hoechst dyes stain the DNA of both living and fixed cells and are compatible with immunohistochemistry applications.

Hoechst 33258 is slightly more water soluble than Hoechst 33342, but both have been used extensively to stain live cells. The products may be used in fluorescence microscopy, micro-plate, cuvette, and flow cytometry applications. Nuclear yellow (Hoechst S769121) is more commonly used as a neuronal retrograde tracer.14-16 Figure 2.

Hoechst (bisbenzimide, HOE) is a family of cell-permeant fluorescent dyes that binds strongly to adenine-thymine-rich regions in the minor groove of double-stranded DNA. Although Hoechst dyes can bind to all nucleic acids, AT-rich dsDNA strands considerably enhance their …