Spastic paraplegia type 11 is part of a group of genetic disorders known as hereditary spastic paraplegias. These disorders are characterized by progressive muscle stiffness (spasticity) …

Mar 27, 2008 · Spastic paraplegia 11 (SPG11) is characterized by progressive spasticity and weakness of the lower limbs frequently associated with the following: mild intellectual disability …

Among the autosomal recessive forms of HSP (AR-HSP), hereditary spastic paraplegia type 11 is the most common one. We present a patient with diagnosed HSP 11, with a typical clinical …

However, the most common form of AR HSP (50%) is caused by mutation of the SPG11 gene, which leads to an uncomplicated or slightly complicated form of HSP. Distinguishing factors of …

Jul 12, 2017 · The hereditary spastic paraplegias (HSP) are a large group of inherited neurologic disorders that share the primary symptom of difficulty walking due to muscle weakness and …

Aug 15, 2000 · Clinical Characteristics and Recommended Treatment: Hereditary Spastic Paraplegia. The predominant signs and symptoms of hereditary spastic paraplegia (HSP) are …

Aug 22, 2024 · Hereditary spastic paraplegia is a genetic condition that causes weakness and muscle tightness in your legs. There are over 80 different types. It’s progressive and can affect …

Spastic paraplegia 11 (SPG11) is the most common cause of autosomal recessive HSP and is the major cause of HSP with a thin corpus callosum (HSP‐TCC), accounting for 41% of HSP‐TCC …

Hereditary spastic paraplegia type 11 (SPG11) is the most common subtype of autosomal recessive hereditary spastic paraplegia (HSP), to date, there are more than 181 different …

Hereditary spastic paraplegia (SPG or HSP) is characterized by progressive weakness and spasticity of the lower limbs due to degeneration of corticospinal axons. SPG11 is a form of …