Human chorionic gonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing embryo (syncytiotrophoblast initially), which eventually forms the placenta after implantation. [1][2] The presence of hCG is detected in some pregnancy tests (HCG pregnancy strip tests).

Human chorionic gonadotropin (hCG) is produced primarily by differentiated syncytiotrophoblasts, and represents a key embryonic signal that is essential for the maintenance of pregnancy. hCG can activate various signaling cascades including mothers against decapentaplegic homolog 2 (Smad2), protein kinase C (PKC), and/or protein kinase A (PKA) i...

Aug 14, 2023 · HCG is an important hormone in pregnancy, and its clinical utility is primarily centered around its detection in early pregnancy, along with serial measurement during pregnancy and pregnancy-related complications. Levels of hCG can vary widely between women with normal pregnancies.

Human chorionic gonadotropin (hCG) has four major isoforms: classical hCG, hyperglycosylated hCG, free β subunit, and sulphated hCG. Classical hCG is the first molecule synthesized by the embryo. Its RNA is transcribed as early as the eight-cell ...

Nov 7, 2022 · hCG is a pregnancy-specific hormone that is critical for the development of the fetus and placenta. Villous syncytiotrophoblasts and trophoblastic cells mainly produce hCG from implantation to the completion of pregnancy at various levels.

One of the key molecules during this process is human chorionic gonadotropin (HCG). HCG effectively modulates several metabolic pathways within the decidua contributing to endometrial receptivity. Herein, a brief overview of the molecular mechanisms regulated by HCG is presented.

Mar 11, 2022 · Human chorionic gonadotropin (hCG) is a hormone produced by the placenta during pregnancy. It helps thicken a person’s uterine lining to support a growing embryo and tells the body to stop menstruation. HCG levels rise after conception and continue to rise until about 10 weeks in pregnancy. What is human chorionic gonadotrophin?

hCG is an hormone produced by the placenta during the pregnancy. It is characterized by a similar structure to LH and it is used to induce follicles maturation and to trigger ovulation, which occurs approximately 36 h after administration.

May 1, 2010 · The first known human embryo-derived signal is chorionic gonadotropin (hCG) by which the embryo profoundly influences immunological tolerance and angiogenesis at the maternal–fetal interface. hCG levels coincide with the development of trophoblast tolerance.

hCG has numerous functions. hCG promotes progesterone production by corpus luteal cells; promotes angiogenesis in uterine vasculature; promoted the fusion of cytotrophoblast cell and differentiation to make syncytiotrophoblast cells; causes the blockage of any immune or macrophage action by mother on foreign invading placental cells; causes ...