Dec 2, 2019 · Here, we show that the imprinted Arabidopsis thaliana MADS-box TF PHERES1 (PHE1) is a master regulator of paternally expressed imprinted genes, as well as of non-imprinted key regulators of endosperm development.

Jun 1, 2020 · Batista et al. identified the type I MADS-box transcription factor (TF) PHERES1 (PHE1) as a key regulator of some imprinted and nonimprinted genes required for endosperm development.

PHE1 is an imprinted gene that is paternally expressed in the developing seed (Köhler et al., 2003b). Although the phe1 single mutant does not show an aberrant phenotype, down-regulation of PHE1 in a mea mutant does partially rescue the …

Mar 15, 2008 · Imprinting of the plant gene PHERES1 requires the function of the FERTILIZATION INDEPENDENT SEED (FIS) Polycomb group (PcG) complex for repression of the maternal PHERES1 allele. In this study we investigated the mechanism of PHERES1 imprinting and found that PcG silencing is necessary but …

In this study, we show that PHE1 and PHE2 are differentially regulated and that the presence of the repeats is essential for imprinting establishment at the PHE1 locus. Based on these data, we propose a model explaining how the different modes of PHE1 and PHE2 regulation evolved.

Dec 2, 2019 · PHE1 binding sites show distinct epigenetic modifications on maternal and paternal alleles, correlating with parental-specific transcriptional activity. Importantly, we show that the CArG-box-like DNA-binding motifs that are bound by PHE1 have been distributed by RC/Helitron transposable elements.

As in the fis class mutants, the Polycomb group (PcG) complex target gene PHERES1 (PHE1) is expressed at higher levels in Atubp26 ovules than in wild type; there is a lower level of H3K27me3 at the PHE1 locus.

Dec 26, 2004 · We recently showed that the MEA-FIE complex is associated with the promoter of the type I MADS-box gene PHERES1 (PHE1) and directly controls PHE1 expression 9. Here, we addressed the question...

Here we show that the MADS-box gene PHERES1 (PHE1) is commonly deregulated in the fis -class mutants. PHE1 belongs to the evolutionarily ancient type I class of MADS-box proteins that have not yet been assigned any function in plants.

Dec 2, 2019 · Here, we show that the imprinted Arabidopsis thaliana MADS-box TF PHERES1 (PHE1) is a master regulator of paternally expressed imprinted genes, as well as of non-imprinted key regulators of endosperm development.