NCI-H1650 [H-1650, H1650] is a cell line exhibiting epithelial morphology that was isolated in 1987 from the lung tissue of a 27-year-old, male smoker with stage 3B, bronchoalveolar carcinoma. Use these cells for your immuno-oncology and lung cancer research.

Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma. Properties of resistant cells generated from lung cancer cell lines treated with EGFR inhibitors. The Cancer Cell Line Encyclopedia enables predictive modelling of …

Mar 21, 2012 · Our results indicate that the EGFR mutation in H1650 cells at least partially bypasses the PTEN deficiency in driving cell growth and survival and that such a downstream mutation does not confer an absolute resistance to EGFR inhibition.

NCI-H1650-GAS-Luc2 is a luciferase reporter-labeled cell line that endogenously expresses a high level of B7 homolog 3 protein (B7-H3). This reporter cell line is useful for monitoring the activity of IFNγ-induced GAS signal transduction pathways.

Jul 17, 2018 · Western blot analysis was employed to detect tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression levels in H1650 cells. In the present study, H1650 cells were treated with TRAIL siRNA or an empty plasmid vector control, followed by gefitinib treatment to investigate apoptosis.

Purpose: H1650 non-small cell lung cancer (NSCLC) cells display primary resistance to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) although they have a deletion mutation on exon 19 of the EGFR gene.

The NCI-H1650 cell line is derived from a human non-small cell lung carcinoma (NSCLC), specifically adenocarcinoma, and is widely used in cancer research due to its distinctive genetic profile and relevance in drug testing.

Jan 5, 2022 · Cell information for NCI-H1650. Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

High molecular weight genomic DNA isolated from NCI-H1650 ATCC CRL-5883 a human bronchoalveolar carcinoma cell line.

Aliases: NCI-H1650, NCIH1650, H1650, CVCL_1483; Tissue: Lung; Cellosaurus: CVCL_1483; NCI-H1650 is in CellMinerCDB, a searchable tool integrating cancer cell line pharmacogenomics data to link gene and drug activity signatures.