Nov 4, 2022 · TP53 mutation exhibits a promising potential for discriminating AML patients with a worse prognosis, thus being capable of serving as a novel tool for prognostication and therapeutic decision-making in the management of AML.

Jul 11, 2022 · Qin, Y. et al. Epigenetic silencing of miR-137 induces drug resistance and chromosomal instability by targeting AURKA in multiple myeloma. Leukemia 31, 1123–1135 (2017).

Jul 11, 2022 · Inhibiting glycine utilization via SLC6A9 knockdown or the treatment with betaine suppresses MM cell proliferation and enhances the effects of bortezomib on MM cells. Together, we identify glycine as a key metabolic regulator of MM, unveil molecular mechanisms governing MM progression, and provide a promising therapeutic strategy for MM treatment.

Guoxiang Qin. Affiliation. School of Electronics and Communication Engineering, Sun Yat-sen University, Shenzhen, China. Publication Topics Bytes Of Data,Characteristics Of Data,Controller Area Network,Conventional Detection Methods,Deep Neural Network,Denial Of Service,Detection Framework,Detection Methods,Detection Of Types,Detection Window ...

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Mutations of the tumor protein p53 (TP53) gene were considered to be associated with an unfavorable prognosis in acute myeloid leukemia (AML). This meta-analysis aimed to systematically elucidate the prognostic value of TP53 mutation in adult patients with AML.

Apr 4, 2024 · In the present work, a dual-functional self-cleaning film is proposed through the design of polydimethylsiloxane (PDMS) nanopillar array, swelling absorption of anatase-typed TiO2 nanoparticles, and final low-surface-energy modification of 1H,1H,2H,2H-perfluorodecyltrimethoxysilane (PFDTS).

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