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  1. Fibroblast growth factor 1 - Wikipedia

    Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene. [5] [6] It is synthesized as a 155 amino acid polypeptide, whose mature form is a non-glycosylated 17-18 kDa protein.

  2. FGF1 Gene - GeneCards | FGF1 Protein | FGF1 Antibody

    Mar 30, 2025 · FGF1 (Fibroblast Growth Factor 1) is a Protein Coding gene. Diseases associated with FGF1 include Common Peroneal Nerve Lesion and Overnutrition. Among its related pathways are Downstream signaling of activated FGFR2 and Apoptotic Pathways in …

  3. Parkinson's Trial of FGF-1 to Spur Blood Vessel Growth in Brain...

    Jan 17, 2022 · Zhittya Genesis Medicine plans to launch what it is calling a “Compassionate Use Clinical Trial” of FGF-1, a biological compound aiming to stimulate new blood vessel growth in the brain, for people with mild-to-moderately severe Parkinson’s disease.

  4. The FGF family: biology, pathophysiology and therapy - PMC

    FGF1 has some therapeutic potential for cardiovascular disorders. Phase I trials have shown that intramyocardial injection of FGF1 during coronary artery bypass graft surgery improves collateral artery growth and capillary proliferation 85 .

  5. FGF/FGFR signaling in health and disease

    Sep 2, 2020 · Fibroblast growth factors (FGFs) are broad-spectrum mitogens and regulate a wide range of cellular functions, including migration, proliferation, differentiation, and survival. It is well...

  6. Fibroblast Growth Factors: Biology, Function, and Application for ...

    Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation.

  7. FGF1 fibroblast growth factor 1 [ Homo sapiens (human) ]

    Feb 8, 2025 · Title: Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated Cells. Expression and function of fibroblast growth factor 1 in the hypertrophied ligamentum flavum of lumbar spinal stenosis.

  8. FGF1 fibroblast growth factor 1 [ (human)] - National Center for ...

    FGF1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. FGF1 is implicated in the occurrence of cleft palate.

  9. Metabolic Messengers: fibroblast growth factor 1 - Nature

    Jun 9, 2022 · Here, we provide an overview of the known metabolic functions of endogenous FGF1 and discuss its therapeutic potential, distinguishing between peripherally or centrally administered FGF1.

  10. FGF1 - a new weapon to control type 2 diabetes mellitus

    Unexpectedly, fibroblast growth factor 1 (FGF1) and its low mitogenic variants have emerged as potentially safe candidates for restoring euglycaemia, without causing overt adverse effects. In particular, a single peripheral injection of FGF1 can lower glucose to normal levels within hours, without the risk of hypoglycaemia.

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