Dec 2, 2021 · Herein, we report Fe-curcumin-based nanoparticles (Fe-Cur NPs) with nanozyme functionalities in guiding the intracellular ROS scavenging and meanwhile exhibiting anti-inflammation efficacy for curing ALI.

14 hours ago · In a prior study, oxidative activation of Fe-PyC3A and concomitant MRI signal increase was shown to be directly linked to oxidation downstream of ROS release from myeloid cells 30. The ex vivo and ...

Dec 17, 2013 · We describe the different roles of iron in triggering cell death, targets of iron-dependent ROS that mediate cell death and a new form of iron-dependent cell death termed ferroptosis.

Sep 1, 2019 · In this review, we first focus on how iron catalyses reactive oxygen species (ROS). Next, we discuss the roles of iron in cell death and senescence and, in particular, the downstream signalling pathways of ROS. Finally, we discuss the potential regulation mechanism of iron as a therapeutic target for various iron-related diseases.

Jul 3, 2019 · All aerobic life requires management of reactive oxygen species (ROS), which damage cellular components. Cells generate ROS endogenously when flavin, quinol, or iron cofactors are autoxidized. ROS damage DNA, certain …

Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of molecules with oxidizing properties known as ROS. Despite those molecules being implied negatively in aging and numerous diseases, their key role in cellular signaling is evident.

Fe–S clusters are implicated in ROS production by Complexes I, II and III. Cluster N2 required for oxygen-sensing in the pulmonary arteries and carotid body. Fe–S clusters emerging as novel therapeutic targets in the treatment of diseases.

Aug 31, 2021 · The generation of reactive oxygen species (ROS) and subsequent hydroxyl radical (·OH)-mediated lipid peroxidation culminating with plasma membrane damage are the core events leading to...

2 days ago · Heterogeneous Fenton stands out as one of the most promising technologies for water decontamination, but its application is limited by the low reaction kinetics due to sluggish Fe(II) generation and mass transfer. Herein, we propose a novel photoassisted Fenton system employing Fe-oxalate confined into CuNi2Al-LDH (CNAL-0.8Fe(C2O4)x), aiming to accelerate reactive oxygen species (ROS)-involved ...

Fe single-atom catalysts (h 3-FNCs) with high loading, high catalytic activity and high stability were synthesized via a method capable of increasing both the metal loading and mass-specific activity by exchanging zinc with iron.