The FKBP s, or FK506 binding proteins, constitute a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function, though not in amino acid sequence. [1] .

Nov 18, 2021 · FK506-binding proteins (FKBPs) belong to the immunophilin family. Like other immunophilins many FKBPs possess a cis-trans peptidyl-prolyl isomerase (PPIase) activity. In …

FK506 binding protein 5, also known as FKBP5, is a protein which in humans is encoded by the FKBP5 gene. [5] The protein encoded by this gene is a member of the immunophilin protein …

Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene. [5] . It is also commonly referred to as FKBP-12 or FKBP12 and is a member …

FK506 binding proteins (FKBPs) are a family of highly conserved proteins in eukaryotes. The prototype of this protein family, FKBP12, is the binding partner for immunosuppressive drugs …

Jan 1, 2018 · FKBP (FK506 Binding Protein), Table 1 FKBP classification with synonyms of gene and protein. In the 1970s, after a decade from the purification of cyclosporine, a selective …

Aug 1, 2011 · FKBPs participate in cancer cellular processes. FKBPs are implicated in cell growth and survival and apoptotic signaling pathways. FKBP51 provide a relevant tissue marker of …

FK506 binding (FKBP) proteins are part of the highly conserved immunophilin family and its members have fundamental roles in the regulation of signalling pathways involved in …

Since FK506-binding proteins (FKBP) were first identified, much progress has been made in understanding the mechanisms involved in regulating the immunological process, steroid …

Jul 14, 2023 · We found that FKBP5 inhibition promoted β-cell survival, improved insulin secretion, and upregulated β-cell functional gene expressions (MAFA and NKX6.1) in acute …