Mar 30, 2025 · EN2 (Engrailed Homeobox 2) is a Protein Coding gene. Diseases associated with EN2 include Autism Spectrum Disorder and Alacrima, Achalasia, And Impaired Intellectual Development Syndrome . Among its related pathways is Dopaminergic neurogenesis .

Mar 30, 2025 · In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal.

Mar 30, 2025 · This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems.

Mar 30, 2025 · NCBI Gene Summary for GSX2 Gene Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Predicted to be involved in generation of neurons; olfactory bulb development; and regulation of transcription by RNA polymerase II.

Symbol Description Category UniProt ID GIFtS GC id Score; 1: EN2: Engrailed Homeobox 2: Protein Coding: P19622: 55: GC07P163754: 45.21: 2: EN2-DT: EN2 Divergent ...

Mar 30, 2025 · GBX2 (Gastrulation Brain Homeobox 2) is a Protein Coding gene. Diseases associated with GBX2 include Opitz Gbbb Syndrome and Charge Syndrome. Among its related pathways are Gastrulation and Nervous system development. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor …

Mar 28, 2025 · ASCL1 (Achaete-Scute Family BHLH Transcription Factor 1) is a Protein Coding gene. Diseases associated with ASCL1 include Haddad Syndrome and Congenital Central Hypoventilation Syndrome. Among its related pathways are Signaling by NTRKs and Nuclear Events (kinase and transcription factor activation).

Mar 30, 2025 · NPW (Neuropeptide W) is a Protein Coding gene. Diseases associated with NPW include Colorectal Adenocarcinoma and Amyloidosis, Hereditary Systemic 1 . Among its related pathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors) .

Complete information for EN2-DT gene (RNA Gene), EN2 Divergent Transcript, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium

Mar 30, 2025 · IRX3 (Iroquois Homeobox 3) is a Protein Coding gene. Diseases associated with IRX3 include Macular Dystrophy, Retinal, 3 and Cycloplegia. Among its related pathways is FTO obesity variant mechanism. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is IRX1.