Mar 28, 2025 · EIF4A1 (Eukaryotic Translation Initiation Factor 4A1) is a Protein Coding gene. Diseases associated with EIF4A1 include Leukemia, Acute Myeloid and Hematologic Cancer. Among its related pathways are Peptide chain elongation and Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S.

Mar 30, 2025 · SENP3-EIF4A1 (SENP3-EIF4A1 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity.

Showing 25 of 8,556 results for EIF4A1 Search Time: 0 ms in Aliases & Descriptions Drugs & Compounds Disorders Text-Mined Disorders Domains Expression in Human Tissues Function Genomics Localization Orthologs Paralogs Pathways Phenotypes Proteins Publications Summaries Transcripts Variants in category Protein Coding RNA Gene Functional Element ...

Mar 30, 2025 · SENP3 EIF4A1 piR-32214-275 SENP3-EIF4A1 MPDU1-AS1: GH17J008172: Promoter/Enhancer: 2.6 : RefSeq EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER: 42.60: 110.05 +613.0: 170: 5.2: ZNF622 KLF6 SP1 HDAC2 MGA ZBTB26 PRDM1 KLF17 POLR2A HCFC1: VAMP2 SNORD118 TMEM107 LOC105371520 ENSG00000266824 lnc-VAMP2-5 DVL2 CNTROB CTC1 WRAP53: GH17J007565: Promoter ...

Mar 30, 2025 · Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase.

Mar 28, 2025 · Interacts mutually exclusive with EIF4A1 or EIF4A2 (PubMed:11408474). Interacts with NGDN and PIWIL2 (By similarity). Component of the CYFIP1-EIF4E-FMR1 complex composed of CYFIP, EIF4E and FMR1 (By similarity).

Mar 28, 2025 · An important paralog of this gene is EIF4A1. UniProtKB/Swiss-Prot Summary for EIF4A2 Gene ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.

Mar 28, 2025 · EIF4A3 (Eukaryotic Translation Initiation Factor 4A3) is a Protein Coding gene. Diseases associated with EIF4A3 include Robin Sequence With Cleft Mandible And Limb Anomalies and Cortical Dysplasia, Complex, With Other Brain Malformations 13.Among its related pathways are Nervous system development and Processing of Capped Intron …

Mar 28, 2025 · Interacts with eIF3 complex, mutually exclusive with EIF4A1 or EIF4A2, EIF4E and through its N-terminus with PABPC1 (PubMed:10970864, 10996799, 12086624, 16698552, 7651417, 7935836, 9372926, 9857202).

Mar 30, 2025 · snord10 eif4a1 cd68 snora67 hsalng0114325 pir-52509-001 mpdu1 dvl2 pfas ctc1 - Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer …