Erdheim-Chester disease (ECD) is a rare systemic xanthogranulomatous, non-Langerhans histiocytic disease that most commonly affects the long bones and visceral organs but often has signs of ocular involvement.

Erdheim-Chester disease (ECD) is a rare blood disorder that occurs when your body makes too many white blood cells called histiocytes. ECD can affect multiple organs and cause various symptoms or even no symptoms, making diagnosis tricky.

Jul 26, 2020 · Ophthalmologists have to be aware of the disease, recognize the constellation of ECD symptoms, and contribute to the diagnosis, treatment, and follow-up of ECD patients. Erdheim–Chester disease (ECD) is a rare disease with less than 1200 documented cases.

Erdheim-Chester disease (ECD) is a rare L-group histiocytosis. Orbital involvement is found in a third of cases, but few data are available concerning the radiological features of ECD-related orbital disease (ECD-ROD).

The condition of the corneal endothelium can be influenced by a number of factors, including systemic diseases, such as diabetes or atherosclerosis, eye diseases, such as uveitis or dry eye disease (DED) and therapeutic ophthalmological interventions.

ECD patients can also present with ocular symptoms as a result of adverse effects of the treatment regimens. In some cases with smoldering or protean symptoms, the emergence of eye manifestations triggered the diagnosis.

Sep 5, 2024 · To review all cases of Erdheim–Chester disease (ECD) with orbital involvement treated at Bascom Palmer Eye Institute in Miami, Florida from 2014 to 2022 and compare presentations, treatment modalities, and outcomes.

Outline Anatomy and function of the eye and orbit Background and overview of ECD What can ECD do to the eye? Double Double vision vision Pain Exophthalmos Overview of an eye exam

Ophthalmic involvement in ECD has been reported in only 22 cases. We describe two patients, one presenting with diabetes insipidus and subsequently developing orbital pseudotumours and...

Purpose: To evaluate corneal endothelial cell density (ECD) in patients with dry eye disease (DED) compared to an age-matched control group. Design: Cross-sectional, controlled study. Methods: This study included 90 eyes of 45 patients with moderate to severe DED (aged 53.7 ± 9.8 years) and 30 eyes of 15 normal controls (aged 50.7 ± 9.8 years).