The TGA/DSC 3+ can be equipped with a SDTA, DTA or DSC sensor for simultaneous detection of thermal effects that do not show a weight loss. Thermogravimetry (TGA) is a technique that measures the change in weight of a sample as it is heated, cooled or held at constant temperature. Its ma...

Mar 30, 2025 · DSC3 (Desmocollin 3) is a Protein Coding gene. Diseases associated with DSC3 include Hypotrichosis And Recurrent Skin Vesicles and Hereditary Hypotrichosis With Recurrent Skin Vesicles. Among its related pathways are Keratinization and Nervous system development.

Desmocollin-3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily.

Desmocollin 3 (DSC3), a member of the cadherin superfamily and integral component of desmosomes, is involved in carcinogenesis. However, the role of DSC3 in colorectal cancer (CRC) has not yet been established. Desmocollin 3 expression in CRC cell lines was analysed by RT–PCR and western blotting.

A homozygous nonsense mutation in the human desmocollin-3 (DSC3) gene underlies hereditary hypotrichosis and recurrent skin vesicles. Ayub M, et al . Am J Hum Genet, 2009 Oct. PMID 19765682, Free PMC Article

Mar 5, 2024 · Mutations in this gene are a cause of hypotrichosis and recurrent skin vesicles disorder. The protein can act as an autoantigen in pemphigus diseases, and it is also considered to be a biomarker for some cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

May 15, 2019 · Desmocollin 3 (DSC3) is a transmembrane adhesion protein of desmosomes and involved in carcinogenesis in various cancer types. Downregulation of DSC3 has been reported in colorectal cancer (CRC). However, the function of DSC3 in CRC has not yet been elucidated.

The DSC uses a robust and versatile DSC sensor with 56/120 thermocouples which guarantees simultaneous outstanding resolution and sensitivity. Modular concept. Protects your investment and fulfills your current and future needs. Simple FlexCal® calibration. Saves time and results in precise and accurate measurements.

Mar 15, 2011 · P53 appears to have an important role in regulating DSC3 expression. DNA methylation contributes to downregulation of DSC3 in CRC cell lines. Methylation status of DSC3 DNA is a prognostic marker for CRC.

In this study, we examined the prevalence of epigenetic silencing of DSC3 gene expression in primary breast tumor specimens. Methods: We used bisulfite genomic sequencing to analyze the methylation state of the DSC3 promoter region from 32 primary breast tumor specimens.