Mar 28, 2025 · COPZ1 (COPI Coat Complex Subunit Zeta 1) is a Protein Coding gene. Diseases associated with COPZ1 include Autoinflammation And Autoimmunity, Systemic, With Immune …

Coatomer subunit zeta-1 is a protein that in humans is encoded by the COPZ1 gene. [5]

Feb 9, 2025 · COPZ1 regulates ferroptosis through NCOA4-mediated ferritinophagy in lung adenocarcinoma. Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in …

Jan 8, 2021 · Herein, we identified coatomer protein complex subunit zeta 1 (COPZ1) as a therapeutic target candidate which significantly dysregulated iron metabolism in GBM cells.

Jan 7, 2024 · Tandem affinity purification and mass spectrometry analysis identify subunit zeta 1 of coatomer protein complex (COPZ1), HIV-1 Gag, Gag/Pol, gp120, and Nef incorporated into …

Dec 6, 2024 · We have identified a new inherited bone marrow (BM) failure syndrome with severe congenital neutropenia (CN) caused by autosomal recessive mutations in the coatomer protein …

COPZ1 is a prognostic marker in Liver hepatocellular carcinoma, Lung adenocarcinoma, Uterine corpus endometrial carcinoma

Results: High expression of COPZ1 was indicative of malignancy and poor overall survival. Clinical LUAD tissues showed increased COPZ1 expression and decreased nuclear receptor …

Jun 7, 2004 · The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate …

The deduced 177-amino acid protein contains a clathrin adaptor complex small chain (see 603531) signature. Low to moderate COPZ1 expression was present in all cell lines examined. …