Chromatin remodeling is the dynamic modification of chromatin architecture to allow access of condensed genomic DNA to the regulatory transcription machinery proteins, and thereby …

Mar 24, 2021 · Lastly, chromatin is dynamic and changes in histone occupancy, histone modifications, and accessibility of DNA contribute to epigenetic regulation. This chapter …

Jul 6, 2017 · There is much research into whether changes in chromatin folding can explain why thousands of variants in regions of the genome that do not encode proteins are linked to …

2 days ago · Chromatin topology can impact gene regulation. Here, Wu et al. show that evolutionary changes in chromatin structure, particularly CTCF loops, can drive distinct …

In the next sections, we highlight the latest scientific findings that have enabled us to better understand the chromatin changes produced after DNA replication and the mechanisms …

Jun 1, 2020 · In this short review, we describe changes of chromatin structure during various biological processes from a DNA sequence view, with an increase of the overall domain …

1 day ago · Changes in the chromatin landscape affect the developmental dynamics of embryogenesis. To assess how perturbations in the epigenetic landscape, resulting from CBP …

Jan 16, 2025 · Chromatin, the physiological template of the eukaryotic genome, has emerged as a sensor and rheostat for fluctuating intracellular metabolites. In this review, we highlight the …

6 hours ago · Chromatin states undergo dynamic changes throughout embryogenesis, which have been analyzed at the bulk level (7, 8). However, owing to the high heterogeneity and limited …

The physiological effects caused by such broad chromatin changes are complex and the cell’s responses to it can be profound and in turn influence the aging process. In this review, we …