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  1. CDC6 - Wikipedia

    Cell division control protein 6 homolog is a protein that in humans is encoded by the CDC6 gene. [5] [6] The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a …

  2. CDC6 Gene - GeneCards | CDC6 Protein | CDC6 Antibody

    Mar 28, 2025 · CDC6 (Cell Division Cycle 6) is a Protein Coding gene. Diseases associated with CDC6 include Meier-Gorlin Syndrome 5 and Meier-Gorlin Syndrome 1. Among its related …

  3. CDC6: from DNA replication to cell cycle checkpoints and …

    Nov 28, 2007 · Cell division cycle 6 (CDC6) is an essential regulator of DNA replication in eukaryotic cells. Its best-characterized function is the assembly of prereplicative complexes at …

  4. CDC6 gene - MedlinePlus

    The CDC6 gene provides instructions for making a protein that is important in the copying of a cell's DNA before the cell divides (a process known as DNA replication). Learn about this gene …

  5. The structure of ORC–Cdc6 on an origin DNA reveals the …

    Jun 23, 2021 · Here we report the cryo-EM structure at 3.3 Å resolution of the yeast ORC–Cdc6 bound to an 85-bp ARS1 origin DNA. The structure reveals that Cdc6 contributes to origin …

  6. Cdc6 as a novel target in cancer: Oncogenic potential, senescence …

    In this review, we summarise the evidence for the role of Cdc6 overexpression in cancer, specifically that of pancreatic cancer. More importantly, we recapitulate the role of Cdc6 as …

  7. CDC6 cell division cycle 6 [ (human)] - National Center for ...

    Jan 4, 2025 · CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma. FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma Through …

  8. CDC6 cell division cycle 6 [ Homo sapiens (human) ]

    Feb 8, 2025 · Title: CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma. FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma …

  9. CDC6 regulates both G2/M transition and metaphase-to-anaphase ... - PubMed

    The results indicate that CDC6 is indispensable for maintaining G2 arrest of meiosis and functions in G2/M checkpoint regulation in mouse oocytes. Moreover, CDC6 is also a key player …

  10. The Cdc6 Nucleotide–Binding Site Regulates Its Activity in DNA ...

    In this study, we have investigated the ability of purified human Cdc6 (HsCdc6), expressed in the baculovirus system as a GST-tagged recombinant protein, to bind and hydrolyze ATP. We …