Invitrogen Anti-CD140b (PDGFRB) Monoclonal (APB5), eBioscience™, Catalog # 14-1402-82. Tested in Immunohistochemistry (Frozen) (IHC (F)) and Flow Cytometry (Flow) applications. This antibody reacts with Mouse samples. Supplied as 100 µg purified antibody (0.5 mg/mL).

Platelet-derived growth factor receptor beta is a protein that in humans is encoded by the PDGFRB gene. Mutations in PDGFRB are mainly associated with the clonal eosinophilia class of malignancies. The PDGFRB gene is located on human chromosome 5 at position q32 (designated as 5q32) and contains 25 exons.

Our data demonstrate a substantial role for CD140b in the intrinsic abilities of ASCs and their angiogenic influence on HREs. Future studies are needed to fully explore the signaling of CD140b in ASCs in vivo for retinal regeneration. Keywords: Mesenchymal stem cells, Pericyte, Endothelial, PDGF, Migration, Retina.

Choose from 1 of 93 PDGFRB (CD140b) antibodies, which have been validated in experiments with 738 publications and 540 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.

To address these issues, we investigated whether CD140b and CD73 could be used as markers for hiPSC-EPO cells. We measured the expression of EPO, CD140b, and CD73 in hiPSC-EPO cells and the EPO concentration in the cell supernatant by immunohistochemistry and enzyme-linked immunosorbent assays on culture day 13, revealing that expression levels ...

Reacts with platelet derived growth factor (PDGF) receptor β, a 170-190 kDa single transmembrane glycoprotein expressed on fibroblasts, smooth muscle cells, glial cells and chondrocytes. PDGF receptors, α and β, are single glycoproteins with intracellular tyrosine kinase domains. They are structurally similar to M-CSF receptor and CD117 (c-kit).

CD140b plays a role in the regulation of embryonic development, cell proliferation, differentiation, chemotaxis, survival, and migration. CD140b is expressed on embryonic tissues and mesenchymal-derived cells in adult mice.

Description eta chain (PDGFRβ). CD140b is a single-pass type I transmembrane glycoprotein that contains an intracellular ty osine kinase domain. This receptor is encoded by Pdgfrb and is widely expressed on cells within embryonic tissues and cells of mesenchymal origin in the adult mouse including fibroblasts and vascular

The role of CD140b [platelet-derived growth factor receptor- β (PDGFR-β)], a constitutive marker expressed by ASCs, in the angiogenic behavior of human retinal endothelial cells (HREs) is not known. CD140b was knocked down in ASCs using targeted siRNA and …

A translocation between chromosomes 5 and 12, that fuses PDGFRB (CD140b) to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.