CD135 is the receptor for the cytokine Flt3 ligand (FLT3L). It is expressed on the surface of many hematopoietic progenitor cells. Signalling of FLT3 is important for the normal development of …

In this study, we determined the cell-surface expression of the FLT3 receptor (CD135) on the blast population and retrospectively analyzed whether expression was correlated with disease …

The aim of this study was to evaluate the frequencies of CD135 and CD117 expressions in leukemic blast cells, the degree of CD135 and CD117 co-expression (CD135+CD117), and …

The FLT3 receptor (Fms-like tyrosine kinase 3), also known as FLK2 (fetal liver tyrosine kinase 2), STK-1 (stem cell tyrosine kinase 1) or CD135, is encoded by the FLT3 gene located on …

Fms-Like Tyrosine Kinase 3 (Flt3) also known CD135 is the receptor for Flt3-Ligand (Flt3L) that is critical for the development and differentiation of cDC and pDC subsets. cDC1s express higher …

CD135 Antigen In subject area: Medicine and Dentistry The Flt3 receptor is a single transmembrane protein and has an extracellular region composed of five immunoglobulin-like …

CD135 (flt3/flk2) Antibodies. The CD135 antigen, also called FLT3 or FLK2 or STK1, is an integral transmembrane glycoprotein of 130 kDa to 150 kDa, which belongs to the class III receptor …

CD135 expression ≥ 25% was a predictor of FLT3-ITD mutation (P = .03). CD135 overexpression was a negative predictor of complete remission and of postinduction minimal residual disease …

CD135 is emerging as a prognostic factor, a new marker for minimal residual disease, and a potential novel therapeutic target of AML.

CD135 is an important cell surface marker used to identify certain types of hematopoietic (blood) progenitors in the bone marrow. Specifically, multipotent progenitors (MPP) and common …