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Cell surface antigens of human ovarian and endometrial carcinoma defined by mouse monoclonal antibodies. Morphological, biological, biochemical, and karyotypic characteristics of human pancreatic ductal adenocarcinoma Capan-2 in tissue culture and the nude mouse. Human tumor lines for cancer research.

Capan-2 is a human pancreatic ductal adenocarcinoma cell line. These cells grow in adherent tissue culture and display epithelial morphology. They form well-differentiated tumors when injected into immunocompromised mice and are used as a xenograft model for pancreatic cancer.

Matsuo et al. showed that BxPC-3 cells secreted high levels of IL-1α and IL-8 whereas Capan-2 and MIA PaCa-2 cells secreted much lower levels of IL-8 and undetectable levels of IL-1α 76.

Capan-2 is a cell line with polygonal morphology that was isolated in 1975 from the pancreas of a 56-year-old, White, male patient with pancreatic adenocarcinoma.

Spotlight on Capan-2 Learn more about this cell line in our scientific spotlights: More than 90% of all pancreatic cancers are classified as ductal adenocarcinomas and, within the western-world, pancreatic cancer is the fourth leading cause of cancer related deaths.

Nov 1, 1986 · Human pancreatic ductal adenocarcinoma Capan-2, derived from a 56-yr-old male Caucasian, has been studied in both tissue culture and the nude.

The Capan-2 cell line is a human pancreatic adenocarcinoma cell line first isolated from the pancreatic tumor tissue of a 56-year-old Caucasian male. It was derived from the metastatic site in the liver, indicating its origin from a secondary tumor which…

The Capan-2 cells express mutant K-Ras (G12V) and elevated levels of the Epidermal Growth Factor Receptor (EGFR). In addition, they express wildtype p53 and normal levels of SMAD4 protein. Application: 3D cell culture; High-throughput screening; Toxicology; Bioproduction; Cancer research

Capan-2 is a human pancreatic ductal adenocarcinoma cell line that was initially derived in 1975 from a primary tumor of a 56-year-old Caucasian male. These cells demonstrate an epithelial morphology and grow in adherent tissue culture.