Aldosterone synthase - Wikipedia
The enzyme catalyzes sequential hydroxylations of the steroid angular methyl group at C18 after initial 11β-hydroxylation (the enzyme has steroid 18-hydroxylase activity as well as steroid 11 …
CYP11B2 Gene - GeneCards | C11B2 Protein | C11B2 Antibody
Mar 30, 2025 · CYP11B2 (Cytochrome P450 Family 11 Subfamily B Member 2) is a Protein Coding gene. Diseases associated with CYP11B2 include Corticosterone Methyloxidase Type …
CYP11B2 gene - MedlinePlus
The CYP11B2 gene provides instructions for making an enzyme called aldosterone synthase (previously known as corticosterone methyloxidase). Learn about this gene and related health …
IMMUNOHISTOCHEMISTRY OF THE HUMAN ADRENAL CYP11B2 …
The CYP11B2 enzyme is the terminal enzyme in the biosynthesis of aldosterone. Immunohistochemistry using antibodies against CYP11B2 defines cells of the adrenal ZG that …
Molecular and Epigenetic Control of Aldosterone Synthase, CYP11B2 …
Angiotensin II or potassium regulates the aldosterone synthase gene, CYP11B2. The adrenocorticotropic hormone controls the 11b-hydroxylase, CYP11B1. DNA methylation …
The clinical significance of aldosterone synthase deficiency: report …
Aldosterone synthase (CYP11B2) deficiency is a rare autosomal recessive disorder, usually presenting with severe salt-wasting in infancy or stress-induced hyperkalaemia and postural …
CYP11B2 cytochrome P450 family 11 subfamily B member 2 …
Apr 7, 2025 · Title: Association between Aldosterone Synthase (CYP11B2) Gene Polymorphism and Hypertension in Pashtun Ethnic Population of Khyber Pakhtunkwha, Pakistan. Functional …
CYP11B2 cytochrome P450 family 11 subfamily B member 2
Nov 2, 2024 · Clinical resource with information about CYP11B2, Corticosterone 18-monooxygenase deficiency, Corticosterone methyloxidase type 2 deficiency, and available …
Analysis of the Aldosterone Synthase (CYP11B2) and 11β
The aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) enzymes are known to be important players in the development of hypertension. Sequencing of the CYP11B2 and …
The potential of targeting CYP11B - PubMed
CYP11B1 catalyzes the formation of cortisol, while CYP11B2 realizes the biosynthesis of aldosterone. Overproduction of cortisol is related to Cushing's disease, whereas …
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