C-X-C motif chemokine 11 (CXCL11) is a protein that in humans is encoded by the CXCL11 gene. [4] C-X-C motif chemokine 11 is a small cytokine belonging to the CXC chemokine family that is also called Interferon-inducible T-cell alpha chemoattractant (I-TAC) and Interferon-gamma-inducible protein 9 (IP-9).

Mar 30, 2025 · CXCL11 (C-X-C Motif Chemokine Ligand 11) is a Protein Coding gene. Diseases associated with CXCL11 include Nasal Cavity Adenocarcinoma and Mycosis Fungoides. Among its related pathways are MIF Mediated Glucocorticoid Regulation and …

CXCL11, also known as interferon-inducible T-cell alpha chemoattractant (I-TAC) or interferon-gamma-inducible protein 9 (IP-9), is induced by IFN-γ and IFN-β, and weakly by IFN-α. [23]

CXCL11 is known as a regulator that influences T-cell infiltration into tumors. However, the role of CXCL11 in pan-cancer is still unclear. In this study, we investigated the expression and function of CXCL11 across 33 types of cancers based on datasets from The Cancer Genome Atlas (TCGA) database and the Genotype-Tissue Expression (GTEx) database.

Jul 1, 2023 · Besides, several evidences indicated that CXCL11, which regulated the chemotaxis of cells and induced infiltration of tumor-associated macrophages, was also one of the key chemokines providing a...

CXCL11 was mildlylavage fluid during diffuse alveolar damage, but not during acute rejection or lymphocytic bronchiolitis. Elevated CXCL11 was associated with increased risk of chronic allograft dysfunction.

Mar 27, 2024 · In this review, we summarize the biological functions of CXCL11 and its receptors and their roles in various types of malignant tumors and point out the directions for clinical applications. CXCL11 is found in many types of cancer and affects how cancer cells grow and respond to treatments.

Oct 28, 2024 · Gene target information for CXCL11 - C-X-C motif chemokine ligand 11 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

CXCL11 which can bind to two different chemokine receptors, CXCR3 and CXCR7, has found a prominent place in current tumor research. In this chapter, we mainly discuss the current evidence on the role of the immune response of CXCL11 in tumor microenvironment (TME).

CXCL9, CXCL10, and CXCL11 lack glutamic acid-leucine-arginine (ELR), and are unique, because they are more closely related to each other than to any other chemokine. The aforementioned chemokines are especially involved in Th1-type response and in various diseases, as their expression correlates with the tissue infiltration of T cells.