Comment: Tumor cells show positive immunostaining for PAX8, CAIX and keratin CAM 5.2. CK7 is negative arguing against clear cell papillary renal cell tumor. Kidney, radical nephrectomy: Clear cell renal cell carcinoma, WHO / ISUP grade 3, measuring 2.5 cm in greatest dimension (see comment) Tumor is confined within the renal capsule.

Oct 8, 2024 · Luminal cells are positive for CK7 Basal cells are positive for p40, p63 and CK5 Defined by identifying NUTM1 or NUTM2B fusions with BRD4 interacting partners (i.e., BRD3, NSD3) and excluding extracutaneous NUT carcinoma Has metastatic potential but is much less aggressive than extracutaneous NUT carcinoma (J Cutan Pathol 2024;51:424)

Cervix: CEA CK7 estrogen receptor (ER) GATA3 HIK1086 HPV Ki67 MUC6 p16 p40 p53 p63 PAX8 progesterone receptor (PR) vimentin Ovary: AE1/AE3 AFP ARID1A calretinin CK7 CD30 EMA estrogen receptor (ER) folate receptor alpha (FRa) (pending) FOXL2 Glypican 3 hCG HNF-1B (pending) inhibin Napsin A OCT 3/4 p16 p53 PAX8 progesterone receptor (PR) PTEN ...

Jun 13, 2022 · The biopsy demonstrates a poorly differentiated malignant neoplasm. An immunohistochemical panel comprising CK7, CK20, CK5/6, TTF1, p40, napsin, calrentin and BerEP4 is performed. Which profile supports the diagnosis of squamous cell carcinoma? CK7+, TTF1+, napsin+, other stains negative

Sep 28, 2021 · A. CK7, CK20, CDX2, SATB2 and PAX8. Low grade appendiceal mucinous neoplasm is usually positive for CK20, CDX2 and SATB2 and negative for CK7 and PAX8. Comment Here Reference: Mucinous cystadenoma / adenofibroma

Jun 1, 2014 · CK7. CK5 / 6. Calretinin. Positive stains. Cytokeratin AE1 / AE3, cytokeratin 7 (CK7) Calretinin (nuclear ...

Mar 23, 2025 · Stains - Cytokeratin 17 (CK17, K17) Distinguish pancreatobiliary adenocarcinoma (CK17+) from extra-pancreatobiliary nonmucinous adenocarcinoma (CK17-, Am J Surg Pathol 2005;29:359)

Feb 16, 2022 · A panel of immunohistochemistry stains show tumor cells to be positive for CD10 and RCC Ma, while being negative for CK7, CK20, PAX8, CD117 and CAIX. While the immunohistochemistry profile is not entirely concordant with a renal primary, especially with negative PAX8 and CAIX, the positivity of both CD10 and RCC Ma would suggest possibility of ...

CK7 positive (however, sometimes patchy in eosinophilic chromophobe) S100A1 usually negative Hybrid oncocytic / chromophobe tumors (HOCT) (Mod Pathol 2019;32:1698): Term usually applied in syndromic settings as the Birt-Hogg-Dubé associated tumors but occasionally sporadic cases can present as such

Aug 23, 2022 · Usually positive for CK7, PAX8, napsin A and HNF1β and negative for ER, PR and WT1, with aberrant p53 expression in up to 24% of cases May be associated with endometriosis or Lynch syndrome Stage is the most important prognostic factor