CD163 (C luster of D ifferentiation 163) is a protein that in humans is encoded by the CD163 gene. [5] CD163 is the high affinity scavenger receptor for the hemoglobin - haptoglobin …

CD163 Structure CD163 is a 130-kDa membrane protein with a short cytoplasmic tail, a single transmembrane segment, and a large ectodomain consisting of nine scavenger receptor …

Jul 17, 2025 · CD163 (CD163 Molecule) is a Protein Coding gene. Diseases associated with CD163 include Histiocytic Sarcoma and Necrobiosis Lipoidica. Among its related pathways are …

Apr 29, 2025 · CD163 is a scavenger receptor expressed on specific macrophages, playing a key role in immune regulation and inflammation resolution. It clears hemoglobin-haptoglobin …

Jul 18, 2025 · CD163 is a receptor used by macrophages to capture and detoxify serum haptoglobin-haemoglobin. Here, the authors show that CD163 adopts a multimeric base that …

Jan 22, 2009 · The plasma membrane glycoprotein receptor CD163 is a member of the scavenger receptor cystein-rich (SRCR) superfamily class B that is highly expressed on resident tissue …

Aug 16, 2019 · Development of CD163 + BMRMs is strictly dependent on IFN regulatory factor-8. CD163 + BMRMs show a specific transcriptome and cytokine secretion pattern demonstrating …

Jun 10, 2013 · The diagnostic and therapeutic properties of CD163 await further clinical studies and regulatory approval before implementation in the clinic.

Oct 11, 2024 · Soluble CD163 (sCD163) is a circulating inflammatory mediator, indicative of acute and chronic, systemic and non-systemic inflammatory conditions. It is the cleavage outcome, …

Jan 1, 2006 · CD163 is a member of the cysteine-rich scavenger receptor family and is exclusively expressed by cells of monocyte/macrophage lineage. 7 Resident tissue …