ITGAM Gene - GeneCards | ITAM Protein | ITAM Antibody
Dec 25, 2024 · This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing …
Integrin alpha M - Wikipedia
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (α M β 2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 …
CD11b Marker: Roles in Immunity and Clinical Relevance
Feb 11, 2025 · CD11b is a critical marker in immunology, primarily associated with myeloid cells. Its significance extends beyond basic research, influencing our understanding of immune …
16409 - Gene ResultItgam integrin alpha M [ (house mouse)]
Feb 19, 2025 · CD11b+ macrophages play an important role in intraperitoneal lipopolysaccharides-induced aberrant lymphangiogenesis and lymphatic dysfunction in the …
ITGAM integrin subunit alpha M [Homo sapiens (human)] - Gene …
Jan 4, 2025 · CD11b is a therapy resistance- and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia. Rhein P, et al. Blood, 2010 May 6. PMID …
CD11b is a therapy resistance– and minimal residual …
May 6, 2010 · CD11b positivity conferred a 5-fold increased risk of minimal residual disease (MRD) after induction therapy (day 33) and of high-risk group assignment after consolidation …
A Novel Genetic Model of Constitutively Active Integrin CD11b…
We genetically targeted the Itgam gene (which codes for CD11b) to introduce a point mutation that results in the I332G substitution in the protein. The I332G mutation in CD11b promotes an …
CD11b Gene - genomics-online.com | cDNA | ORF | Primers | Kits
Short Description: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
The CD11b-integrin (ITGAM) and systemic lupus erythematosus
Variations at the ITGAM gene, which encodes for the CD11b chain of the Mac-1 (alphaMbeta2; CD11b/CD18; complement receptor-3) integrin, is one of the strongest genetic risk factors for …
The promoter of the CD11b gene directs myeloid-specific and ...
Jan 1, 2001 · To begin to understand the mechanisms by which expression of these gene products is restricted to leukocytes and leukocyte subpopulations and to elucidate the …