Cytospins prepared from flow-sorted tumor-infiltrating HLA-DR hi and HLA-DR int CD11b + CD14 + cells showed that HLA-DR hi CD14 + cells typically demonstrated the morphology of …

The kit depletes T cells, B cells, NK cells, dendritic cells, granulocytes, and erythrocytes, while the negatively isolated human monocytes are left in the sample. If cell sorting instrumentation is …

Mature monocytes are positive for CD11b, CD11c, CD13, CD14, CD33, and CD64, and may express CD2 and CD4. Blasts in acute myeloid leukemias (AML) with minimal differentiation …

Sep 30, 2015 · We have devised an internally standardized flow cytometry approach that can identify parallel inflammatory alveolar macrophage phenotypes in both the mouse and human …

Jul 6, 2016 · In human peripheral blood mononuclear cell (PBMC), the equivalent to PMN-MDSC are defined as CD11b + CD14 − CD15 + or CD11b + CD14 − CD66b + and M-MDSC as …

The increased expression of CD11b could explain some of the side-effects during treatment with rhGM-CSF. The upregulation of CD14 induced by rhG-CSF may be clinically relevant, as …

In this review, we will discuss known mechanisms underlying the therapeutic efficiency of CD14, TLR4, and CD11b/CD18 antibodies with a focus on LPS-dependent ROS or cytokine …

Monocytes that have diminished or no HLA-DR expression, called CD14 + HLA-DR lo/neg monocytes, have emerged as important mediators of tumor-induced immunosuppression.

Jan 15, 2014 · Here we report that the integrin α M (CD11b) positively regulates LPS-induced signalling pathways selectively in myeloid dendritic cells but not in macrophages. In dendritic …

Jan 1, 2001 · The role of CD11b/CD18 might be analogous to that of CD14, where CD11b/CD18 functions to bind Taxol (via CD18) and LPS, whereas associated TLR4 molecules function as …