Nov 12, 2024 · BioBridge™ is an innovative nanofibrillar scaffold with a multi-luminal structure that promotes lymph flow via a capillary effect and guides lymphatic endothelial cell migration and lymphatic capillary organization.

Aug 21, 2024 · This study aimed to assess the preventive and therapeutic efficacy of BioBridge (Fibralign Corp., Union City, CA, USA) implantation and its potential to induce lymphangiogenesis in an animal model.

BioBridge is a sterile implantable biocompatible and biodegradable surgical mesh ribbon comprised of highly purified porcine collagen that is designed to provide mechanical support for weaknesses...

In animals with confirmed lymphedema (4–5 weeks after lymph node resection and irradiation), after induction of anesthesia, the animals receive implantations of five BioBridge devices following a similar design as the prevention model.

Other groups incorporated recombinant VEGF-C in nanofibrillar collagen scaffolds to support collateral lymphatic formation across the obstructed area (BioBridge™) . Animals treated with the device had decreased extracellular fluid accumulation 3 months after surgery.

Sep 1, 2016 · The BioBridge scaffold may act by inducing capillary flow (Suppl., Fig. 4B–C), and therefore it may provide both acute relief from swelling as well as a favorable condition for lymphangiogenesis. BioBridge provides a suitable environment for endothelial cells.

In addition, emerging adjunctive strategies are explored, specifically evidence from animal and pilot human studies regarding implantation of a collagen nanofibrillar scaffold (BioBridge™; Fibralign Corporation, Union City, CA) in promoting lymphangiogenesis, preventing and treating lymphedema, and enhancing outcomes with lymphaticovenous ...

Background: We tested our hypothesis that implantation of aligned nanofibrillar collagen scaffolds (BioBridge™) can both prevent and reduce established lymphedema in the rat lymphedema model.

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BioBridge Blood Pressure Monitor provides remote monitoring for patients with implanted cardiac devices, allowing healthcare providers to focus on patient care.